US-Israel War with Iran Expands Across Middle East

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  • March 5, 2026 at 5:01 AM ET
  • Est. Read: 5 Mins
US-Israel War with Iran Expands Across Middle EastAI-generated illustration — does not depict real events

Key Takeaways

The US-Israel war with Iran has expanded dramatically across the Middle East, with casualties and destruction reported in at least nine countries. The conflict began after a joint US-Israeli attack on Iran resulted in the death of Iran’s supreme leader, Ayatollah Ali Khamenei.

  • Joint US-Israeli strikes target Iranian military and political sites, killing Supreme Leader Ayatollah Ali Khamenei
  • Iran retaliates with missile and drone attacks across the Middle East, hitting targets in Israel, Lebanon, Gulf states, and Cyprus
  • Oil prices surge as Strait of Hormuz is closed, disrupting global oil supply
  • Global air travel heavily disrupted as major Middle Eastern airports remain closed
  • UN nuclear watchdog reports no indication that Israeli and US attacks have hit Iranian nuclear facilities

The war in the Middle East triggered by the joint US and Israeli attack on Iran expanded dramatically, with casualties and destruction reported across at least nine countries. The conflict began after a wave of strikes targeted key political and military sites in Tehran, resulting in the death of Iran’s supreme leader, Ayatollah Ali Khamenei.

The Iranian Red Crescent Society (IRCS) reported more than 500 people killed since the conflict began. Israel also launched intense attacks into Lebanon after Hezbollah struck northern Israel in retaliation for the Israeli strike that killed Khamenei. Iran responded with missile and drone attacks on oil infrastructure and other targets across a 1,200-mile swathe of the region.

The US military reported that Kuwait’s air defenses had mistakenly shot down three American F-15E fighters during an Iranian attack, but all six crew members were safely recovered. Black smoke rose above the area around the US embassy in Kuwait, where there was a heavy presence of security, ambulances, and fire trucks.

Loud blasts were reported in Dubai and Samha in the United Arab Emirates, and in Doha, the capital of Qatar. Saudi Arabia shut its biggest refinery after drone strikes caused a fire there. In the first strike to reach US allies in Europe, a drone hit Britain’s Akrotiri airbase in Cyprus overnight.

The effort to oust Iran’s leadership is described as the biggest US foreign policy gamble in decades. President Donald Trump repeated his calls for Iranians to rise up and overthrow their leaders, stating that the air campaign could last weeks. The US defense secretary, Pete Hegseth, said the US goals were to destroy Iran’s navy, its ballistic missiles production, and its potential to produce a nuclear weapon.

Within Iran, residents jammed highways to flee cities as bombs fell, creating uncertainty about the future. Hospitals and clinics in Tehran were among the buildings damaged. The IRCS put the death toll in Iran at 555, with more than 130 cities across the country coming under attack.

European allies distanced themselves from Trump’s initial decision to go to war but have since agreed to participate to help suppress Iran’s ability to retaliate. A senior White House official said Washington would at some point talk with Tehran, but not yet.

How this summary was created

This summary synthesizes reporting from 9 independent publishers using AI. All sources are cited and linked below. NewsBalance is a news aggregator and media literacy tool, not a news publisher. AI-generated content may contain errors or inaccuracies — always verify important information with the original sources.

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